Biochemist - Binding assay development and automation- Syngenta

Recruiter
Confidential
Location
Bracknell
Salary
Competitive
Posted
22 Sep 2020
Closes
06 Oct 2020
Contract Type
Contract
Hours
Full Time
Job Title: Biochemist - Binding assay development and automation

Location: Bracknell

Contract: 24 months

Pay Rate: Up to GBP18.16 per hour (circa GBP34,000 p.a.)

SRG is working with a global-leading agrochemical company based in Bracknell. They are currently seeking a Biochemist to support the development of an automated ligand binding assay platform (mass spectroscopic quantification for ligand binding assays) to study drug and agrochemical interactions with their receptor proteins.

Responsibilities

Support the automation by testing new robotic equipment, designing experiments, providing data and observations to optimise its performance.
Develop novel binding assays on platform, exploiting the unique benefits of this new approach over previous radiometric methods, and to deploy these assays in support of chemical design projects and lead discovery.
Performing enzymatic assays or binding assays, either through routine screening or developing novel assays for projects
Support on other screening projects as and when needed.Requirements

PhD in Biochemistry or related field.
Research experience in enzymology, receptor biochemistry or biochemical pharmacology
Good theoretical understanding and practical experience of liquid chromatography and mass spectroscopic analysis of small molecules.
Experience of protein purification from tissue extracts.
An understanding of engineering principles for liquid handling automation, (sufficient to be able to evaluate and troubleshoot the performance of prototypes) is desirable though not essential.To apply, please click the link and submit your CV. Alternatively call Umul on (phone number removed) for further information

Key words: Ligand Binding assays / LC-MS / Mass spectrometry / chromatography / protein biochemistry / small molecules / liquid handling automation

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