Process Development Scientist

Due to continued growth, our client has an exciting opportunity for a Process Development Scientist to join its team. Your focus will be on Downstream Processing to support its DNA manufacturing platform technology. To be considered, you must have proven experience in a commercial lab environment and be familiar with bioprocessing techniques.

Role description:

You will play an important role in the development of dbDNATMmanufacturing process. This will involve working in a team focussed on optimising and validating production processes, establishing critical parameters and controls; industrial scale up and technical transfer of methods to third parties/GMP production team.

This position will be highly collaborative, within the CMC function and also with production and R&D teams. In addition, the candidate will be expected to interact with clients, outside collaborators and contractors as required.

Qualifications and experience:

Essential:

• A PhD level qualification in Biochemistry / Protein chemistry / Molecular Biology or equivalent industrial experience.
• In addition, experience of CMC/process development in a pharmaceutical setting.
• Familiarity with bioprocessing techniques, such as chromatography, tangential flow filtration and filtration.
• Familiarity with standard Molecular Biology techniques such as cloning, PCR, mutagenesis and in related specialised DNA characterisation techniques.
• Experience in keeping accurate and thorough records of laboratory experiments as well as experience of writing technical reports to a good standard.
• Applicants must be reliable, enthusiastic, self-motivated and have an ability to learn new techniques quickly.

Desirable:

• Experience in process characterisation, qualification and validation.
• Familiarity with the use of enzymatic processes in an industrial setting.
• Proficiency with design of experiments software and techniques would be beneficial.
• Experience with taking a risk based approach to process development.