Scientist/Senior Scientist - HTS Biology
- Recruiter
- Charles River Laboratories
- Location
- Saffron Walden
- Salary
- Competitive
- Posted
- 25 Jun 2022
- Closes
- 02 Jul 2022
- Sectors
- Scientific & Pharmaceutical
- Contract Type
- Permanent
- Hours
- Full Time
For 70 years, Charles River employees have worked together to assist in the discovery, development and safe manufacture of new drug therapies. When you join our family, you will have a significant impact on the health and well-being of people across the globe. Whether your background is in life sciences, finance, IT, sales or another area, your skills will play an important role in the work we perform. In return, we'll help you build a career that you can feel passionate about.
**Job Summary**
Charles River are looking for dynamic and self-motivated Scientists/Senior Scientists, who are ready to advance their career to the next level by joining our growing HTS Department. The roles will be based at our Chesterford Park site, although you will be expected to interact across the CRL Early Discovery sites (Leiden in the Netherlands and Harlow in the UK), and with a diverse range of clients across the world.
*Further Responsibilities:*
• To develop, optimize and execute in-vitro biological assays (both biochemical and cellular) for HTS drug discovery projects.
• To lead or have a significant influence on the execution and aspects of strategy for hit finding in drug discovery projects.
• To ensure client projects are delivered to time, proactively resolving issues when they arise.
• To QC equipment and data - using your experience to troubleshoot assays.
• To present own work (and that of others where appropriate) to clients and internal audiences, confidently with clear rationale.
• To maintain an active interest in novel drug discovery screening techniques and disease area literature, applying these findings to current and potential future projects.
• To ensure that all work is conducted in a safe manner, complying with all CRL site-based guidelines.
The ideal candidate will have a degree level qualification, coupled with relevant experience (ideally gained within industry or an academic screening environment). You will have a passion for applying your scientific expertise to drug discovery collaborations and be enthusiastic about working at the bench.
You will be working on a range of biochemical and cellular assay formats, solving challenging problems, analysing, and reporting data to advance client projects aimed at discovering new medicines.
This role will place you as part of a cross-functional team working at the forefront of drug discovery, interacting with other groups across the organisation including computational chemistry, chemistry, compound management and DMPK.
*About Discovery*
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350patents and 80preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.
*About Charles River*
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increasedto $2.62billion.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.
**Job Summary**
Charles River are looking for dynamic and self-motivated Scientists/Senior Scientists, who are ready to advance their career to the next level by joining our growing HTS Department. The roles will be based at our Chesterford Park site, although you will be expected to interact across the CRL Early Discovery sites (Leiden in the Netherlands and Harlow in the UK), and with a diverse range of clients across the world.
*Further Responsibilities:*
• To develop, optimize and execute in-vitro biological assays (both biochemical and cellular) for HTS drug discovery projects.
• To lead or have a significant influence on the execution and aspects of strategy for hit finding in drug discovery projects.
• To ensure client projects are delivered to time, proactively resolving issues when they arise.
• To QC equipment and data - using your experience to troubleshoot assays.
• To present own work (and that of others where appropriate) to clients and internal audiences, confidently with clear rationale.
• To maintain an active interest in novel drug discovery screening techniques and disease area literature, applying these findings to current and potential future projects.
• To ensure that all work is conducted in a safe manner, complying with all CRL site-based guidelines.
The ideal candidate will have a degree level qualification, coupled with relevant experience (ideally gained within industry or an academic screening environment). You will have a passion for applying your scientific expertise to drug discovery collaborations and be enthusiastic about working at the bench.
You will be working on a range of biochemical and cellular assay formats, solving challenging problems, analysing, and reporting data to advance client projects aimed at discovering new medicines.
This role will place you as part of a cross-functional team working at the forefront of drug discovery, interacting with other groups across the organisation including computational chemistry, chemistry, compound management and DMPK.
*About Discovery*
Discovery from Charles River is industry-proven in the successful development of novel therapies, with over 350patents and 80preclinical drug candidates delivered to our sponsors in the past 17 years. Backed by more than 650 scientists, our comprehensive, integrated portfolio employs the latest technology and platforms to provide chemistry, biology, and pharmacology services that support clients from the earliest stages of hit identification all the way through to IND. Our client-focused, collaborative approach creates true partnerships that anticipate challenges, overcome obstacles, and move us forward together on the journey of getting new drugs to market.
*About Charles River*
Charles River is an early-stage contract research organization (CRO). We have built upon our foundation of laboratory animal medicine and science to develop a diverse portfolio of discovery and safety assessment services, both Good Laboratory Practice (GLP) and non-GLP, to support clients from target identification through preclinical development. Charles River also provides a suite of products and services to support our clients' clinical laboratory testing needs and manufacturing activities. Utilizing this broad portfolio of products and services enables our clients to create a more flexible drug development model, which reduces their costs, enhances their productivity and effectiveness to increase speed to market.
With over 17,000 employees within 90 facilities in 20 countries around the globe, we are strategically positioned to coordinate worldwide resources and apply multidisciplinary perspectives in resolving our client's unique challenges. Our client base includes global pharmaceutical companies, biotechnology companies, government agencies and hospitals and academic institutions around the world. And in 2019, revenue increasedto $2.62billion.
At Charles River, we are passionate about our role in improving the quality of people's lives. Our mission, our excellent science and our strong sense of purpose guide us in all that we do, and we approach each day with the knowledge that our work helps to improve the health and well-being of many across the globe. We have proudly supported the development of ~85% of the drugs approved by the FDA in 2019.