Associate Scientist Cell Biology Cell Imunology

Elevate Direct
13.00 - 14.50 GBP Hourly
14 Jan 2021
18 Jan 2021
Contract Type
Full Time

Associate Scientist, Cell Process Development Cell and Gene Therapy Platform

Basic Qualifications:
BSc/MSc in biology, cell biology, immunology or related scientific discipline with at least 1 year of experience in tissue culture techniques

Preferred Qualifications:
Experience in analytical techniques such as flow cytometry
Experience working in cell and gene therapy, process development and/or GMP is desirable
Strong organisational and interpersonal communication skills
Demonstrable ability to work in multi-disciplinary, multi-cultural teams
Demonstrable ability to work independently

GlaxoSmithKline (GSK) is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to create a platform for the delivery for strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better and live longer.

GSK's Cell & Gene Therapy Platform CMC team is being expanded to support an increasing portfolio of cell and gene therapies. The team is responsible for delivering the Chemistry, Manufacturing and Controls (CMC) aspects of the projects from early phase to launch and the development of innovative technologies to enable step-change improvements to cell & gene therapy manufacture.

GSK has secured a significant collaboration in the T cell immunotherapy field with Adaptimmune and other licensing/partnership opportunities are being pursued. The progression of our own portfolio together with the maturation of emerging gene therapy technologies creates an imperative for GSK to now increase our investment in this space and establish an end-to-end leading platform. This will facilitate delivery of the portfolio and ensure that GSK is able to capture the potential of the emerging technologies in other therapeutic areas.

A highly motivated and independent individual is sought to work within the cell process development team.

Your duties will include, but are not limited to:
Work collaboratively with Cell & Gene Therapy Platform CMC cell process research and analytical development scientists to establish the cell process for cell and gene therapies through both well designed experiments performed in-house and through managing experiments to be performed by Contract Manufacturing Organisations (CMOs)
Execute laboratory studies to develop the cell process for autologous cell/ex vivo gene therapies
Conduct studies to develop and validate innovative technologies and approaches to make step-change improvements in process efficiency
Support development of a portfolio of ex vivo gene therapies from early to late stage by executing development work and generating data.
Responsible for compliant, clear and concise documentation and/or presentation of all experimental studies and results
Maintaining good working relationships with third parties (contractors, suppliers, academic and industry groups) to ensure successful process development and/or technology transfer