Primary Cell Transduction Process Scientist

Basic qualifications:
PhD in Biological or Biomedical Sciences, preferably in Virology.
Good understanding of virus-cell interactions.
Experience with mammalian cell culture, preferably stem cell and/or T cell isolation, transduction, expansion.
Experience in use of lentivirus/retrovirus for genetic cell modification.
Experience in cell analysis/characterisation techniques (Flow cytometry, CFU assays, immunocytochemistry, cell differentiation assays).
Experience in assays for gene/protein expression analysis (PCR, qPCR, RT-PCR, WB, etc)
Good organisation and communication skills
Demonstrable ability to work in multi-disciplinary, multi-cultural teams
Demonstrable ability to work independently, plan, organise, troubleshoot and present work

Preferred qualifications:
Experience in Gene Therapy
Knowledge of HIV/Retrovirus biology.
Experience in high-throughput screening of compounds
Experience in cloning, production and titration of lenti/retroviruses
Experience of working in vivo.

Details:
GlaxoSmithKline is a world leading research-based pharmaceutical company that combines both individual talent and technical resources to create a platform for the delivery for strong growth in a rapidly changing healthcare market. Our mission is to improve the quality of human life by enabling people to do more, feel better and live longer.

GSK's Cell and Gene Therapy Platform is being expanded to support an increasing portfolio of cell and gene therapies. The team is responsible for delivering the Chemistry, Manufacturing and Controls (CMC) aspects of the projects from early phase to launch and the development of innovative technologies to enable step-change improvements to cell & gene therapy manufacture.

About the role.
A highly motivated and independent individual is sought to work within the Process Research team, Cell and Gene Therapy Platform. The successful candidate will be expected to:

•Participate in activities related to the understanding and improvement of the cell-virus interactions for the genetic modification of primary cells.

The successful candidate is expected to have a background/experience in Virology and Stem Cell or T cell biology and/or Gene Therapy, preferably with experience in transduction of primary cells. Experience in high throughput screening of biopharmaceutical products, although not required, would be an advantage.

The successful candidate will report to the Transduction Sciences Manager. Their work will however involve collaboration with multiple units within GSK as well as external collaborators. Excellent communication, organisation and presentation skills, as well as demonstrable ability to work effectively in multi-disciplinary and multi-cultural teams are required.

The role will be based in the UK, in Stevenage. The role requires external engagement with 3rd parties (contractors, suppliers, academic and industry groups). As such, experience with working with 3rd parties and management of outsourced work will be an advantage. European and international travel will be required at times, as dictated by the project needs.

When applying for this role, please use the 'cover letter' of the on-line application to describe how you meet the competencies required for this role, as outlined in the job requirements above. The information that you have provided in your cover letter and CV will be used to assess your application.

During the course of your application you will be requested to complete voluntary information which will be used in monitoring the effectiveness of our equality and diversity policies. Your information will be treated as confidential and will not be used in any part of the selection process.

If you require a reasonable adjustment to the application / selection process to enable you to demonstrate your ability to perform the job requirements please contact . This will help us to understand any modifications we may need to make to support you throughout our selection process.

Closing Date for applications:3rd August 2017

Thank you for your interest in this opportunity.

*LI-GSK

Contact information:
You may apply for this position online by selecting the Apply now button.

Important notice to Employment businesses/ Agencies

GSK does not accept referrals from employment businesses and/or employment agencies in respect of the vacancies posted on this site. All employment businesses/agencies are required to contact GSK's commercial and general procurement/human resources department to obtain prior written authorization before referring any candidates to GSK. The obtaining of prior written authorization is a condition precedent to any agreement (verbal or written) between the employment business/ agency and GSK. In the absence of such written authorization being obtained any actions undertaken by the employment business/agency shall be deemed to have been performed without the consent or contractual agreement of GSK. GSK shall therefore not be liable for any fees arising from such actions or any fees arising from any referrals by employment businesses/agencies in respect of the vacancies posted on this site.

Salary: . Date posted: 20/07/2017