T Cell Cloning - Scientist 238

The Company is a leader in the research and development of T cell-based therapies for the treatment of cancer. The business is rapidly growing in both the UK and USA and we have multiple early-phase clinical trials ongoing in oncology centres across both the US and Europe.

The purpose of this role is to primarily conduct scientific experiments as necessary within dedicated scientific teams. Whilst initially requiring supervision by a more senior scientist, the job holder will develop further scientific skills to be able to work more independently on routine experiments. The job holder will also be responsible for the interpretation of scientific results under the supervision of a senior scientist.

Functional focus: The T cell cloning group is concerned with isolating T cell clones against target peptides to start new Pipeline programmes. Desirable skills for this group include lentivirus production, primary cell culture, flow cytometry, cytotoxicity assays and ELISA/ELISpot.

70%: Conducting cell biology techniques such as cell culture of tumour cell lines and primary cells, lentivirus production, PBMC preps and cell subset isolation from whole blood, and some flow cytometry and ELISA/ELISpot to support scientists and the Group as a whole.

20%: Analyse, summarise and record experimental results, and maintain relevant databases and records.

5%: Participate in project meetings and discussions.

5%: R outline lab maintenance.

Required Qualifications and Experience

• Undergraduate degree in Lifesciences or related discipline
• Ability to work independently on routine experiments with limited supervision.
  • Ability to learn and develop in order to work independently on routine experiments within a reasonable time frame.
• Experience of laboratory procedures, with previous cell culture experience (preferably isolation and culture of primary cells).

Desirable

• Additional post-graduate scientific experience or qualifications, such as an M.Sc.

Required Skills and Competencies

• Computer literate and ability to familiarise with different IT systems
• Excellent numeracy and English language skills (both written and verbal)
• Excellent communication skills (both written and verbal)
• Ability to follow protocols.
• Knowledge and skills to use of standard laboratory equipment (such as pipettes, pH meters, centrifuges).
• Basic experimental design skills (use of controls, etc.), attention to detail, good time management skills, team player attitude, good communication skills.
• Able to work independently after training.
• Strong team player but with the ability to work independently as well.

Desirable

• Use of more specialist lab equipment (flow cytometers, ELISA plate readers).

How to Apply

Please click on apply and submit your full CV. Please be aware you are also required to complete an online application form, this will be emailed to you on receipt of your CV.